Biroul LOT Polish Airlines pentru Marfuri si Posta a fost infiintat in 1995 si ofera servicii la cel mai inalt nivel de calitate. LOT Cargo este prezent cu servicii proprii in marile aeroporturi europene, in Statele Unite ale Americii si Canada si cu servicii de interline agreement in toate zonele mapamondului. La ora actuala flota LOT este constituita din 51 aeronave: 15 Boeing cu raza de actiune cuprinsa intre 2.150 si 11.700 kilometri, 22 Embraer cu raza de actiune intre 1.500 si 3.000 km si 14 aeronave ATR cu raza de pana la 1.200 km. In 2012 LOT Polish Airlines va achizitiona patru aeronave Boeing 787 Dreamliner, fiind transportate marfuri non-stop pe distante de pana la 15.200 km. LOT Polish Airlines se identifica cu urmatoarele date: cod IATA / LO ; cod ICAO / LOT; prefix AWB / 080
Destinatiile LOT Polish Airlines cu plecare din Aeroportul Henri Coanda, Bucuresti sunt:
| Aeroport | Cod IATA |
|---|---|
| WARSZAWA | WAW |
| GDANSK | GDN |
| KATOWICE | KTW |
| KRAKOW | KRK |
| POZNAN | POZ |
| RZESZOW | RZE |
| SZCZECIN | SZZ |
| WROCLAW | WRO |
| YEREVAN | EVN |
| KALININGRAD | KGD |
| KIEV | KBP |
| LWOW | LWO |
| MINSK | MSQ |
| MOSCOW | SVO |
| ODESSA | ODS |
| RIGA | RIX |
| ST. PETERSBURG | LED |
| TALLIN | TLL |
| TIBILISI | TBS |
| VILNUS | VNO |
| CHICAGO | ORD |
| NEWARK | EWR |
| NEW YORK | JFK |
| TORONTO | YYZ |
| CAIRO | CAI |
| DAMASCUS | DAM |
| TEL AVIV | TLV |
| HANOI | HAN |
| AMSTERDAM | AMS |
| ATHENS | ATH |
| BARCELONA | BCN |
| BRATISLAVA | BTS |
| BELGRAD | BEG |
| BERLIN | TXL |
| BRUSSELS | BRU |
| BUDAPEST | BUD |
| COPENHAGEN | CPH |
| DUSSELDORF | DUS |
| FRANKFURT | FRA |
| GENEVE | GVA |
| HAMBURG | HAM |
| HELSINKI | HEL |
| LARNACA | LCA |
| ISTANBUL | IST |
| LONDON | LHR |
| MADRID | MAD |
| MILAN | MXP |
| MUNICH | MUC |
| NICE | NCE |
| PARIS | CDG |
| PRAGUE | PRG |
| ROME | FCO |
| SOFIA | SOF |
| STOCKHOLM | ARN |
| VIENNA | VIE |
| ZURICH | ZRH |
| ATLANTA | ATL |
| AUSTIN | AUS |
| BALTIMORE | BWI |
| BOSTON | BOS |
| CHARLOTTE | CLT |
| CINCINATTI | CVG |
| CLEVELAND | CLE |
| DALLAS | DFW |
| DENVER | DEN |
| DETROIT | DTW |
| EL PASO | ELP |
| FORT LAUDERDALE | FLL |
| HOUSTON | IAH |
| INDIANAPOLIS | IND |
| LOS ANGELES | LAX |
| LOUISVILLE | SDF |
| MIAMI | MIA |
| MINNEAPOLIS | MSP |
| NASHVILLE | BNA |
| PHILADELPHIA | PHL |
| PITTSBURG | PIT |
| RALEIGH DURHAM | RDU |
| SAN ANTONIO | SAT |
| SAN FRANCISCO | SFO |
| SEATTLE | SEA |
| ST. LOUIS | STL |
| TUSCON | TUS |
| TULSA | TUL |
| WASHINGTON | IAD |
| CALGARY | YYC |
| EDMONTON | YEG |
| HALIFAX | YHZ |
| MONTREAL | YUL |
| MONCTON | YQM |
| VANCOUVER | YVR |
| WINNIPEG | YWG |